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Discovery and characterization of chromatin states for systematic annotation of the human genome

A plethora of epigenetic modifications have been described in the human genome and shown to play diverse roles in gene regulation, cellular differentiation, and the onset of disease. While some modifications have been linked with activity levels of different functional elements, their combinatorial...

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Detalles Bibliográficos
Autores principales: Ernst, Jason, Kellis, Manolis
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919626/
https://www.ncbi.nlm.nih.gov/pubmed/20657582
http://dx.doi.org/10.1038/nbt.1662