Should the ApoE genotype be a covariate for clinical trials in Alzheimer disease?

Should the apolipoprotein E (ApoE) genotype be a covariate for clinical trials in Alzheimer disease (AD)? ApoE is a transport protein for lipids, amyloid-beta proteins, and the different phenotypes differentially affect amyloid-beta deposition, neurofibrillary tangle formation, and microglial activa...

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Detalles Bibliográficos
Autor principal: Farlow, Martin R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919695/
https://www.ncbi.nlm.nih.gov/pubmed/20537201
http://dx.doi.org/10.1186/alzrt39

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919695/
https://www.ncbi.nlm.nih.gov/pubmed/20537201
http://dx.doi.org/10.1186/alzrt39

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