Equilibrium conformational dynamics in an RNA tetraloop from massively parallel molecular dynamics

Conformational equilibrium within the ubiquitous GNRA tetraloop motif was simulated at the ensemble level, including 10 000 independent all-atom molecular dynamics trajectories totaling over 110 µs of simulation time. This robust sampling reveals a highly dynamic structure comprised of 15 conformati...

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Detalles Bibliográficos
Autores principales: DePaul, Allison J., Thompson, Erik J., Patel, Sarav S., Haldeman, Kristin, Sorin, Eric J.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919701/
https://www.ncbi.nlm.nih.gov/pubmed/20223768
http://dx.doi.org/10.1093/nar/gkq134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919701/
https://www.ncbi.nlm.nih.gov/pubmed/20223768
http://dx.doi.org/10.1093/nar/gkq134

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