Ubc13 dosage is critical for immunoglobulin gene conversion and gene targeting in vertebrate cells

In contrast to lower eukaryotes, most vertebrate cells are characterized by a moderate efficiency of homologous recombination (HR) and limited feasibility of targeted genetic modifications. As a notable exception, the chicken DT40 B cell line is distinguished by efficient homology-mediated repair of...

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Detalles Bibliográficos
Autores principales: Ertongur, Isin, Tomi, Nils-Sebastian, Kutzera, André, Fischer-Burkart, Sabine, Jungnickel, Berit
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919702/
https://www.ncbi.nlm.nih.gov/pubmed/20223767
http://dx.doi.org/10.1093/nar/gkq154

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919702/
https://www.ncbi.nlm.nih.gov/pubmed/20223767
http://dx.doi.org/10.1093/nar/gkq154

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