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The C-terminus of Utp4, mutated in childhood cirrhosis, is essential for ribosome biogenesis
The small subunit (SSU) processome is a large ribonucleoprotein that is required for maturation of the 18S rRNA of the ribosome. Recently, a missense mutation in the C-terminus of an SSU processome protein, Utp4/Cirhin, was reported to cause North American Indian childhood cirrhosis (NAIC). In this...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919705/ https://www.ncbi.nlm.nih.gov/pubmed/20385600 http://dx.doi.org/10.1093/nar/gkq185 |