Cargando…

The distribution of active RNA polymerase II along the transcribed region is gene-specific and controlled by elongation factors

In order to study the intragenic profiles of active transcription, we determined the relative levels of active RNA polymerase II present at the 3′- and 5′-ends of 261 yeast genes by run-on. The results obtained indicate that the 3′/5′ run-on ratio varies among the genes studied by over 12 log(2) uni...

Descripción completa

Detalles Bibliográficos
Autores principales: Rodríguez-Gil, Alfonso, García-Martínez, José, Pelechano, Vicent, Muñoz-Centeno, María de la Cruz, Geli, Vincent, Pérez-Ortín, José E., Chávez, Sebastián
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919717/
https://www.ncbi.nlm.nih.gov/pubmed/20385590
http://dx.doi.org/10.1093/nar/gkq215