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The distribution of active RNA polymerase II along the transcribed region is gene-specific and controlled by elongation factors
In order to study the intragenic profiles of active transcription, we determined the relative levels of active RNA polymerase II present at the 3′- and 5′-ends of 261 yeast genes by run-on. The results obtained indicate that the 3′/5′ run-on ratio varies among the genes studied by over 12 log(2) uni...
Autores principales: | Rodríguez-Gil, Alfonso, García-Martínez, José, Pelechano, Vicent, Muñoz-Centeno, María de la Cruz, Geli, Vincent, Pérez-Ortín, José E., Chávez, Sebastián |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919717/ https://www.ncbi.nlm.nih.gov/pubmed/20385590 http://dx.doi.org/10.1093/nar/gkq215 |
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