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Harnessing Traction-Mediated Manipulation of the Cell-Matrix Interface to Control Stem Cell Fate

Stem cells sense and respond to the mechanical properties of the extracellular matrix. However, both the extent to which extracellular matrix mechanics affect stem cell fate in 3D micro-environments and the underlying biophysical mechanisms are unclear. We demonstrate that the commitment of mesenchy...

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Detalles Bibliográficos
Autores principales: Huebsch, Nathaniel, Arany, Praveen R., Mao, Angelo S., Shvartsman, Dmitry, Ali, Omar A., Bencherif, Sidi A., Rivera-Feliciano, José, Mooney, David J.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919753/
https://www.ncbi.nlm.nih.gov/pubmed/20418863
http://dx.doi.org/10.1038/nmat2732