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Harnessing Traction-Mediated Manipulation of the Cell-Matrix Interface to Control Stem Cell Fate
Stem cells sense and respond to the mechanical properties of the extracellular matrix. However, both the extent to which extracellular matrix mechanics affect stem cell fate in 3D micro-environments and the underlying biophysical mechanisms are unclear. We demonstrate that the commitment of mesenchy...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919753/ https://www.ncbi.nlm.nih.gov/pubmed/20418863 http://dx.doi.org/10.1038/nmat2732 |