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Insights into cerebrovascular complications and Alzheimer disease through the selective loss of GRK2 regulation

Alzheimer disease (AD) and stroke are two leading causes of age-associated dementia. Increasing evidence points to vascular damage as an early contributor to the development of AD and AD-like pathology. In this review, we discuss the role of G protein-coupled receptor kinase 2 (GRK2) as it relates t...

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Detalles Bibliográficos
Autores principales: Obrenovich, Mark E, Morales, Ludis A, Cobb, Celia J, Shenk, Justin C, Méndez, Gina M, Fischbach, Kathryn, Smith, Mark A, Qasimov, Eldar K, Perry, George, Aliev, Gjumrakch
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919803/
https://www.ncbi.nlm.nih.gov/pubmed/19292735
http://dx.doi.org/10.1111/j.1582-4934.2008.00512.x