Inhibiting heat-shock protein 90 reverses sensory hypoalgesia in diabetic mice

Increasing the expression of Hsp70 (heat-shock protein 70) can inhibit sensory neuron degeneration after axotomy. Since the onset of DPN (diabetic peripheral neuropathy) is associated with the gradual decline of sensory neuron function, we evaluated whether increasing Hsp70 was sufficient to improve...

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Detalles Bibliográficos
Autores principales: Urban, Michael J, Li, Chengyuan, Yu, Cuijuan, Lu, Yuanming, Krise, Joanna M, McIntosh, Michelle P, Rajewski, Roger A, Blagg, Brian S J, Dobrowsky, Rick T
Formato: Texto
Lenguaje:English
Publicado: American Society for Neurochemistry 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919983/
https://www.ncbi.nlm.nih.gov/pubmed/20711301
http://dx.doi.org/10.1042/AN20100015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919983/
https://www.ncbi.nlm.nih.gov/pubmed/20711301
http://dx.doi.org/10.1042/AN20100015

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