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Autoprocessing of human immunodeficiency virus type 1 protease miniprecursor fusions in mammalian cells
BACKGROUND: HIV protease (PR) is a virus-encoded aspartic protease that is essential for viral replication and infectivity. The fully active and mature dimeric protease is released from the Gag-Pol polyprotein as a result of precursor autoprocessing. RESULTS: We here describe a simple model system t...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920229/ https://www.ncbi.nlm.nih.gov/pubmed/20667109 http://dx.doi.org/10.1186/1742-6405-7-27 |