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Autoprocessing of human immunodeficiency virus type 1 protease miniprecursor fusions in mammalian cells

BACKGROUND: HIV protease (PR) is a virus-encoded aspartic protease that is essential for viral replication and infectivity. The fully active and mature dimeric protease is released from the Gag-Pol polyprotein as a result of precursor autoprocessing. RESULTS: We here describe a simple model system t...

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Detalles Bibliográficos
Autores principales:	Huang, Liangqun, Chen, Chaoping
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920229/ https://www.ncbi.nlm.nih.gov/pubmed/20667109 http://dx.doi.org/10.1186/1742-6405-7-27

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