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Intensity dependent estimation of noise in microarrays improves detection of differentially expressed genes

BACKGROUND: In many microarray experiments, analysis is severely hindered by a major difficulty: the small number of samples for which expression data has been measured. When one searches for differentially expressed genes, the small number of samples gives rise to an inaccurate estimation of the ex...

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Detalles Bibliográficos
Autores principales: Zeisel, Amit, Amir, Amnon, Köstler, Wolfgang J, Domany, Eytan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920277/
https://www.ncbi.nlm.nih.gov/pubmed/20663218
http://dx.doi.org/10.1186/1471-2105-11-400