CDK8 is a positive regulator of transcriptional elongation within the serum response network

The Mediator complex allows communication between transcription factors and RNA polymerase II (RNAPII). CDK8, the kinase found in some variants of Mediator, has been characterized mostly as a transcriptional repressor. Recently, CDK8 was demonstrated to be a potent oncoprotein. Here we show that CDK...

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Detalles Bibliográficos
Autores principales: Donner, Aaron J., Ebmeier, Christopher C., Taatjes, Dylan J., Espinosa, Joaquín M.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920286/
https://www.ncbi.nlm.nih.gov/pubmed/20098423
http://dx.doi.org/10.1038/nsmb.1752

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920286/
https://www.ncbi.nlm.nih.gov/pubmed/20098423
http://dx.doi.org/10.1038/nsmb.1752

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