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SUMOylation by Pias1 Regulates the Activity of the Hedgehog Dependent Gli Transcription Factors
BACKGROUND: Hedgehog (Hh) signaling, a vital signaling pathway for the development and homeostasis of vertebrate tissues, is mediated by members of the Gli family of zinc finger transcription factors. Hh signaling increases the transcriptional activity of Gli proteins, at least in part, by inhibitin...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920307/ https://www.ncbi.nlm.nih.gov/pubmed/20711444 http://dx.doi.org/10.1371/journal.pone.0011996 |