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A Minimal Model of Signaling Network Elucidates Cell-to-Cell Stochastic Variability in Apoptosis
BACKGROUND: Signaling networks are designed to sense an environmental stimulus and adapt to it. We propose and study a minimal model of signaling network that can sense and respond to external stimuli of varying strength in an adaptive manner. The structure of this minimal network is derived based o...
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Formato: | Texto |
Lenguaje: | English |
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Public Library of Science
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920308/ https://www.ncbi.nlm.nih.gov/pubmed/20711445 http://dx.doi.org/10.1371/journal.pone.0011930 |