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CHL1 Is a Selective Organizer of the Presynaptic Machinery Chaperoning the SNARE Complex

Proteins constituting the presynaptic machinery of vesicle release undergo substantial conformational changes during the process of exocytosis. While changes in the conformation make proteins vulnerable to aggregation and degradation, little is known about synaptic chaperones which counteract these...

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Detalles Bibliográficos
Autores principales: Andreyeva, Aksana, Leshchyns'ka, Iryna, Knepper, Michael, Betzel, Christian, Redecke, Lars, Sytnyk, Vladimir, Schachner, Melitta
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920317/
https://www.ncbi.nlm.nih.gov/pubmed/20711454
http://dx.doi.org/10.1371/journal.pone.0012018