α-Synuclein Suppression by Targeted Small Interfering RNA in the Primate Substantia Nigra

The protein α-synuclein is involved in the pathogenesis of Parkinson's disease and other neurodegenerative disorders. Its toxic potential appears to be enhanced by increased protein expression, providing a compelling rationale for therapeutic strategies aimed at reducing neuronal α-synuclein bu...

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Detalles Bibliográficos
Autores principales: McCormack, Alison L., Mak, Sally K., Henderson, Jaimie M., Bumcrot, David, Farrer, Matthew J., Di Monte, Donato A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920329/
https://www.ncbi.nlm.nih.gov/pubmed/20711464
http://dx.doi.org/10.1371/journal.pone.0012122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920329/
https://www.ncbi.nlm.nih.gov/pubmed/20711464
http://dx.doi.org/10.1371/journal.pone.0012122

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