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Principal Component Analysis of HPLC Retention Data and Molecular Modeling Structural Parameters of Cardiovascular System Drugs in View of Their Pharmacological Activity

Evaluation of relationships between molecular modeling structural parameters and high-performance liquid chromatography (HPLC) retention data of 11 cardiovascular system drugs by principal component analysis (PCA) in relation to their pharmacological activity was performed. The six retention data pa...

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Detalles Bibliográficos
Autores principales: Stasiak, Jolanta, Koba, Marcin, Bober, Leszek, Bączek, Tomasz
Formato: Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920560/
https://www.ncbi.nlm.nih.gov/pubmed/20717530
http://dx.doi.org/10.3390/ijms11072681