Down-regulation of E-cadherin is an essential event in activating β-catenin/Tcf dependent transcription and expression of its target genes in Pdcd4 knock-down cells

We previously reported that knock-down of tumor suppressor Pdcd4 (Programmed Cell Death 4) down-regulates E-cadherin expression and activates β-catenin/Tcf (T cell factor) dependent transcription in colon tumor cells. However, the underlying mechanism of these observations remains unknown. In this s...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Qing, Sun, Zhen-Xiao, Allgayer, Heike, Yang, Hsin-Sheng
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920641/
https://www.ncbi.nlm.nih.gov/pubmed/19784072
http://dx.doi.org/10.1038/onc.2009.302

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920641/
https://www.ncbi.nlm.nih.gov/pubmed/19784072
http://dx.doi.org/10.1038/onc.2009.302

Ejemplares similares