Structural basis for receptor recognition by New World hemorrhagic fever arenaviruses

New World hemorrhagic fever arenaviruses are rodent-borne agents that cause severe human disease. The GP1 subunit of the surface glycoprotein mediates cell attachment through transferrin receptor 1 (TfR1). We report the structure of Machupo virus (MACV) GP1 bound with human TfR1. Atomic details of t...

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Detalles Bibliográficos
Autores principales: Abraham, Jonathan, Corbett, Kevin D, Farzan, Michael, Choe, Hyeryun, Harrison, Stephen C
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920743/
https://www.ncbi.nlm.nih.gov/pubmed/20208545
http://dx.doi.org/10.1038/nsmb.1772

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920743/
https://www.ncbi.nlm.nih.gov/pubmed/20208545
http://dx.doi.org/10.1038/nsmb.1772

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