Autophagy termination and lysosome reformation regulated by mTOR

Autophagy is an evolutionarily conserved process to catabolize cytoplasmic proteins and organelles1, 2. During starvation, the target of rapamycin (TOR), a nutrient-responsive kinase, is inhibited, thereby inducing autophagy. In autophagy, double-membrane autophagosomes envelop and sequester intrace...

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Detalles Bibliográficos
Autores principales: Yu, Li, McPhee, Christina K., Zheng, Lixin, Mardones, Gonzalo A., Rong, Yueguang, Peng, Junya, Mi, Na, Zhao, Ying, Liu, Zhihua, Wan, Fengyi, Hailey, Dale W., Oorschot, Viola, Klumperman, Judith, Baehrecke, Eric H., Lenardo, Michael J.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920749/
https://www.ncbi.nlm.nih.gov/pubmed/20526321
http://dx.doi.org/10.1038/nature09076

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920749/
https://www.ncbi.nlm.nih.gov/pubmed/20526321
http://dx.doi.org/10.1038/nature09076

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