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Autophagy termination and lysosome reformation regulated by mTOR
Autophagy is an evolutionarily conserved process to catabolize cytoplasmic proteins and organelles1, 2. During starvation, the target of rapamycin (TOR), a nutrient-responsive kinase, is inhibited, thereby inducing autophagy. In autophagy, double-membrane autophagosomes envelop and sequester intrace...
Autores principales: | Yu, Li, McPhee, Christina K., Zheng, Lixin, Mardones, Gonzalo A., Rong, Yueguang, Peng, Junya, Mi, Na, Zhao, Ying, Liu, Zhihua, Wan, Fengyi, Hailey, Dale W., Oorschot, Viola, Klumperman, Judith, Baehrecke, Eric H., Lenardo, Michael J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920749/ https://www.ncbi.nlm.nih.gov/pubmed/20526321 http://dx.doi.org/10.1038/nature09076 |
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