Delayed Treatment with Systemic (S)-Roscovitine Provides Neuroprotection and Inhibits In Vivo CDK5 Activity Increase in Animal Stroke Models

BACKGROUND: Although quite challenging, neuroprotective therapies in ischemic stroke remain an interesting strategy to counter mechanisms of ischemic injury and reduce brain tissue damage. Among potential neuroprotective drug, cyclin-dependent kinases (CDK) inhibitors represent interesting therapeut...

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Detalles Bibliográficos
Autores principales: Menn, Bénédicte, Bach, Stéphane, Blevins, Teri L., Campbell, Mark, Meijer, Laurent, Timsit, Serge
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920814/
https://www.ncbi.nlm.nih.gov/pubmed/20711428
http://dx.doi.org/10.1371/journal.pone.0012117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920814/
https://www.ncbi.nlm.nih.gov/pubmed/20711428
http://dx.doi.org/10.1371/journal.pone.0012117

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