Rad21-Cohesin Haploinsufficiency Impedes DNA Repair and Enhances Gastrointestinal Radiosensitivity in Mice

Approximately half of cancer-affected patients receive radiotherapy (RT). The doses delivered have been determined upon empirical experience based upon average radiation responses. Ideally higher curative radiation doses might be employed in patients with genuinely normal radiation responses and imp...

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Detalles Bibliográficos
Autores principales: Xu, Huiling, Balakrishnan, Kuhendra, Malaterre, Jordane, Beasley, Matthew, Yan, Yuqian, Essers, Jeroen, Appeldoorn, Esther, Thomaszewski, Jonathan M., Vazquez, Melisa, Verschoor, Sandra, Lavin, Martin F., Bertonchello, Ivan, Ramsay, Robert G., McKay, Michael J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920816/
https://www.ncbi.nlm.nih.gov/pubmed/20711430
http://dx.doi.org/10.1371/journal.pone.0012112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920816/
https://www.ncbi.nlm.nih.gov/pubmed/20711430
http://dx.doi.org/10.1371/journal.pone.0012112

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