Cargando…

Puma and Trail/Dr5 Pathways Control Radiation-Induced Apoptosis in Distinct Populations of Testicular Progenitors

Spermatogonia- stem cells and progenitors of adult spermatogenesis- are killed through a p53-regulated apoptotic process after γ-irradiation but the death effectors are still poorly characterized. Our data demonstrate that both intrinsic and extrinsic apoptotic pathways are involved, and especially...

Descripción completa

Detalles Bibliográficos
Autores principales: Coureuil, Mathieu, Ugolin, Nicolas, Tavernier, Marie, Chevillard, Sylvie, Barroca, Vilma, Fouchet, Pierre, Allemand, Isabelle
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920820/
https://www.ncbi.nlm.nih.gov/pubmed/20711434
http://dx.doi.org/10.1371/journal.pone.0012134