The SWR1 Histone Replacement Complex Causes Genetic Instability and Genome-Wide Transcription Misregulation in the Absence of H2A.Z

The SWR1 complex replaces the canonical histone H2A with the variant H2A.Z (Htz1 in yeast) at specific chromatin regions. This dynamic alteration in nucleosome structure provides a molecular mechanism to regulate transcription, gene silencing, chromosome segregation and DNA repair. Here we show that...

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Detalles Bibliográficos
Autores principales: Morillo-Huesca, Macarena, Clemente-Ruiz, Marta, Andújar, Eloísa, Prado, Félix
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920830/
https://www.ncbi.nlm.nih.gov/pubmed/20711347
http://dx.doi.org/10.1371/journal.pone.0012143

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920830/
https://www.ncbi.nlm.nih.gov/pubmed/20711347
http://dx.doi.org/10.1371/journal.pone.0012143

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