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Computational Models of HIV-1 Resistance to Gene Therapy Elucidate Therapy Design Principles

Gene therapy is an emerging alternative to conventional anti-HIV-1 drugs, and can potentially control the virus while alleviating major limitations of current approaches. Yet, HIV-1's ability to rapidly acquire mutations and escape therapy presents a critical challenge to any novel treatment pa...

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Detalles Bibliográficos
Autores principales: Aviran, Sharon, Shah, Priya S., Schaffer, David V., Arkin, Adam P.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920833/
https://www.ncbi.nlm.nih.gov/pubmed/20711350
http://dx.doi.org/10.1371/journal.pcbi.1000883