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Computational Models of HIV-1 Resistance to Gene Therapy Elucidate Therapy Design Principles
Gene therapy is an emerging alternative to conventional anti-HIV-1 drugs, and can potentially control the virus while alleviating major limitations of current approaches. Yet, HIV-1's ability to rapidly acquire mutations and escape therapy presents a critical challenge to any novel treatment pa...
Autores principales: | Aviran, Sharon, Shah, Priya S., Schaffer, David V., Arkin, Adam P. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920833/ https://www.ncbi.nlm.nih.gov/pubmed/20711350 http://dx.doi.org/10.1371/journal.pcbi.1000883 |
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