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Polychlorinated Biphenyls Disrupt Intestinal Integrity via NADPH Oxidase-Induced Alterations of Tight Junction Protein Expression

BACKGROUND: Polychlorinated biphenyls (PCBs) are widely distributed environmental toxicants that contribute to numerous disease states. The main route of exposure to PCBs is through the gastrointestinal tract; however, little is known about the effects of PCBs on intestinal epithelial barrier functi...

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Detalles Bibliográficos
Autores principales: Choi, Yean Jung, Seelbach, Melissa J., Pu, Hong, Eum, Sung Yong, Chen, Lei, Zhang, Bei, Hennig, Bernhard, Toborek, Michal
Formato: Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920918/
https://www.ncbi.nlm.nih.gov/pubmed/20299304
http://dx.doi.org/10.1289/ehp.0901751