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Structural Comparison of Human Mammalian Ste20-Like Kinases

BACKGROUND: The serine/threonine mammalian Ste-20 like kinases (MSTs) are key regulators of apoptosis, cellular proliferation as well as polarization. Deregulation of MSTs has been associated with disease progression in prostate and colorectal cancer. The four human MSTs are regulated differently by...

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Detalles Bibliográficos
Autores principales: Record, Christopher J., Chaikuad, Apirat, Rellos, Peter, Das, Sanjan, Pike, Ashley C. W., Fedorov, Oleg, Marsden, Brian D., Knapp, Stefan, Lee, Wen Hwa
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920948/
https://www.ncbi.nlm.nih.gov/pubmed/20730082
http://dx.doi.org/10.1371/journal.pone.0011905