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Polymorphisms in the Base Excision Repair Pathway and Graft-versus-Host Disease

Graft-versus-host disease (GVHD) is a frequent complication after hematopoietic cell transplant (HCT). Tissue damage as a result of chemo-radiation injury is the initiating event in the pathogenesis of acute GVHD. Variations in DNA repair can influence the amount of tissue damage in response to alky...

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Detalles Bibliográficos
Autores principales: Arora, Mukta, Lindgren, Bruce, Basu, Saonli, Nagaraj, Sriharsha, Gross, Myron, Weisdorf, Daniel, Thyagarajan, Bharat
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2921004/
https://www.ncbi.nlm.nih.gov/pubmed/20574454
http://dx.doi.org/10.1038/leu.2010.139