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Polymorphisms in the Base Excision Repair Pathway and Graft-versus-Host Disease
Graft-versus-host disease (GVHD) is a frequent complication after hematopoietic cell transplant (HCT). Tissue damage as a result of chemo-radiation injury is the initiating event in the pathogenesis of acute GVHD. Variations in DNA repair can influence the amount of tissue damage in response to alky...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2921004/ https://www.ncbi.nlm.nih.gov/pubmed/20574454 http://dx.doi.org/10.1038/leu.2010.139 |