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Efficient Inhibition of Collagen-Induced Platelet Activation and Adhesion by LAIR-2, a Soluble Ig-Like Receptor Family Member

LAIR-1 (Leukocyte Associated Ig-like Receptor -1) is a collagen receptor that functions as an inhibitory receptor on immune cells. It has a soluble family member, LAIR-2, that also binds collagen and can interfere with LAIR-1/collagen interactions. Collagen is a main initiator for platelet adhesion...

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Detalles Bibliográficos
Autores principales: Lenting, Peter J., Westerlaken, Geertje H. A., Denis, Cécile V., Akkerman, Jan Willem, Meyaard, Linde
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2921339/
https://www.ncbi.nlm.nih.gov/pubmed/20730098
http://dx.doi.org/10.1371/journal.pone.0012174