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Cdc42 Interaction with N-WASP and Toca-1 Regulates Membrane Tubulation, Vesicle Formation and Vesicle Motility: Implications for Endocytosis

Transducer of Cdc42-dependent actin assembly (Toca-1) consists of an F-BAR domain, a Cdc42 binding site and an SH3 domain. Toca-1 interacts with N-WASP, an activator of actin nucleation that binds Cdc42. Cdc42 may play an important role in regulating Toca-1 and N-WASP functions. We report here that...

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Detalles Bibliográficos
Autores principales: Bu, Wenyu, Lim, Kim Buay, Yu, Yuan Hong, Chou, Ai Mei, Sudhaharan, Thankiah, Ahmed, Sohail
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2921345/
https://www.ncbi.nlm.nih.gov/pubmed/20730103
http://dx.doi.org/10.1371/journal.pone.0012153