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Histone H4 acetylation by immunohistochemistry and prognosis in newly diagnosed adult acute lymphoblastic leukemia (ALL) patients

BACKGROUND: Histone deacetylase (HDAC) inhibitors are a novel anti-tumor therapy. To determine whether HDAC inhibitors may be useful in the treatment of adult acute lymphoblastic leukemia (ALL), we examined the acetylation of histone H4 by immunohistochemistry in newly diagnosed ALL patients and eva...

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Detalles Bibliográficos
Autores principales: Advani, Anjali S, Gibson, Sarah E, Douglas, Elizabeth, Jin, Tao, Zhao, Xiaoxian, Kalaycio, Matt, Copelan, Ed, Sobecks, Ronald, Sekeres, Mikkael, Sungren, Shawnda, Hsi, Eric D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2921396/
https://www.ncbi.nlm.nih.gov/pubmed/20663136
http://dx.doi.org/10.1186/1471-2407-10-387