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Sequence-based identification of interface residues by an integrative profile combining hydrophobic and evolutionary information

BACKGROUND: Protein-protein interactions play essential roles in protein function determination and drug design. Numerous methods have been proposed to recognize their interaction sites, however, only a small proportion of protein complexes have been successfully resolved due to the high cost. There...

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Detalles Bibliográficos
Autores principales: Chen, Peng, Li, Jinyan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2921408/
https://www.ncbi.nlm.nih.gov/pubmed/20667087
http://dx.doi.org/10.1186/1471-2105-11-402