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Plk1 regulates mitotic Aurora A function through βTrCP-dependent degradation of hBora
Polo-like kinase 1 (Plk1) and Aurora A play key roles in centrosome maturation, spindle assembly, and chromosome segregation during cell division. Here we show that the functions of these kinases during early mitosis are coordinated through Bora, a partner of Aurora A first identified in Drosophila....
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Springer-Verlag
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2921497/ https://www.ncbi.nlm.nih.gov/pubmed/18521620 http://dx.doi.org/10.1007/s00412-008-0165-5 |