Plk1 regulates mitotic Aurora A function through βTrCP-dependent degradation of hBora

Polo-like kinase 1 (Plk1) and Aurora A play key roles in centrosome maturation, spindle assembly, and chromosome segregation during cell division. Here we show that the functions of these kinases during early mitosis are coordinated through Bora, a partner of Aurora A first identified in Drosophila....

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Detalles Bibliográficos
Autores principales: Chan, Eunice H. Y., Santamaria, Anna, Silljé, Herman H. W., Nigg, Erich A.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2921497/
https://www.ncbi.nlm.nih.gov/pubmed/18521620
http://dx.doi.org/10.1007/s00412-008-0165-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2921497/
https://www.ncbi.nlm.nih.gov/pubmed/18521620
http://dx.doi.org/10.1007/s00412-008-0165-5

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