Synergy of combined Doxycycline/TUDCA treatment in lowering Transthyretin deposition and associated biomarkers: studies in FAP mouse models

Familial Amyloidotic Polyneuropathy (FAP) is a disorder characterized by the extracellular deposition of fibrillar Transthyretin (TTR) amyloid, with a special involvement of the peripheral nerve. We had previously shown that doxycycline administered for 3 months at 40 mg/Kg/ml in the drinking water,...

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Detalles Bibliográficos
Autores principales: Cardoso, Isabel, Martins, Diana, Ribeiro, Tania, Merlini, Giampaolo, Saraiva, Maria João
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2922089/
https://www.ncbi.nlm.nih.gov/pubmed/20673327
http://dx.doi.org/10.1186/1479-5876-8-74

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2922089/
https://www.ncbi.nlm.nih.gov/pubmed/20673327
http://dx.doi.org/10.1186/1479-5876-8-74

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