The exenatide analogue AC3174 attenuates hypertension, insulin resistance, and renal dysfunction in Dahl salt-sensitive rats

BACKGROUND: Activation of glucagon-like peptide-1 (GLP-1) receptors improves insulin sensitivity and induces vasodilatation and diuresis. AC3174 is a peptide analogue with pharmacologic properties similar to the GLP-1 receptor agonist, exenatide. Hypothetically, chronic AC3174 treatment could attenu...

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Detalles Bibliográficos
Autores principales: Liu, Que, Adams, Lisa, Broyde, Anatoly, Fernandez, Rayne, Baron, Alain D, Parkes, David G
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2922097/
https://www.ncbi.nlm.nih.gov/pubmed/20678234
http://dx.doi.org/10.1186/1475-2840-9-32

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2922097/
https://www.ncbi.nlm.nih.gov/pubmed/20678234
http://dx.doi.org/10.1186/1475-2840-9-32

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