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The exenatide analogue AC3174 attenuates hypertension, insulin resistance, and renal dysfunction in Dahl salt-sensitive rats

BACKGROUND: Activation of glucagon-like peptide-1 (GLP-1) receptors improves insulin sensitivity and induces vasodilatation and diuresis. AC3174 is a peptide analogue with pharmacologic properties similar to the GLP-1 receptor agonist, exenatide. Hypothetically, chronic AC3174 treatment could attenu...

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Detalles Bibliográficos
Autores principales:	Liu, Que, Adams, Lisa, Broyde, Anatoly, Fernandez, Rayne, Baron, Alain D, Parkes, David G
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2922097/ https://www.ncbi.nlm.nih.gov/pubmed/20678234 http://dx.doi.org/10.1186/1475-2840-9-32

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