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Prognostic significance of TRAIL death receptors in Middle Eastern colorectal carcinomas and their correlation to oncogenic KRAS alterations

BACKGROUND: Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) is a member of the tumour necrosis factor cytokine family that induces apoptosis upon binding to its death domain containing receptors, TRAIL receptor 1 (DR4) and TRAIL receptor 2 (DR5). Expression of TRAIL receptors is hig...

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Detalles Bibliográficos
Autores principales: Bavi, Prashant, Prabhakaran, Sarita E, Abubaker, Jehad, Qadri, Zeeshan, George, Thara, Al-Sanea, Nasser, Abduljabbar, Alaa, Ashari, Luai H, Alhomoud, Samar, Al-Dayel, Fouad, Hussain, Azhar R, Uddin, Shahab, Al-Kuraya, Khawla S
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2922191/
https://www.ncbi.nlm.nih.gov/pubmed/20673328
http://dx.doi.org/10.1186/1476-4598-9-203