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Robustness of Ancestral Sequence Reconstruction to Phylogenetic Uncertainty
Ancestral sequence reconstruction (ASR) is widely used to formulate and test hypotheses about the sequences, functions, and structures of ancient genes. Ancestral sequences are usually inferred from an alignment of extant sequences using a maximum likelihood (ML) phylogenetic algorithm, which calcul...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2922618/ https://www.ncbi.nlm.nih.gov/pubmed/20368266 http://dx.doi.org/10.1093/molbev/msq081 |