Ephexin4 and EphA2 mediate cell migration through a RhoG-dependent mechanism

EphA2, a member of the Eph receptor family, is frequently overexpressed in a variety of human cancers, including breast cancers, and promotes cancer cell motility and invasion independently of its ligand ephrin stimulation. In this study, we identify Ephexin4 as a guanine nucleotide exchange factor...

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Detalles Bibliográficos
Autores principales: Hiramoto-Yamaki, Nao, Takeuchi, Shingo, Ueda, Shuhei, Harada, Kohei, Fujimoto, Satoshi, Negishi, Manabu, Katoh, Hironori
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2922637/
https://www.ncbi.nlm.nih.gov/pubmed/20679435
http://dx.doi.org/10.1083/jcb.201005141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2922637/
https://www.ncbi.nlm.nih.gov/pubmed/20679435
http://dx.doi.org/10.1083/jcb.201005141

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