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Ephexin4 and EphA2 mediate cell migration through a RhoG-dependent mechanism
EphA2, a member of the Eph receptor family, is frequently overexpressed in a variety of human cancers, including breast cancers, and promotes cancer cell motility and invasion independently of its ligand ephrin stimulation. In this study, we identify Ephexin4 as a guanine nucleotide exchange factor...
Autores principales: | Hiramoto-Yamaki, Nao, Takeuchi, Shingo, Ueda, Shuhei, Harada, Kohei, Fujimoto, Satoshi, Negishi, Manabu, Katoh, Hironori |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2922637/ https://www.ncbi.nlm.nih.gov/pubmed/20679435 http://dx.doi.org/10.1083/jcb.201005141 |
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