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Drosophila Mtm and class II PI3K coregulate a PI(3)P pool with cortical and endolysosomal functions

Reversible phosphoinositide phosphorylation provides a dynamic membrane code that balances opposing cell functions. However, in vivo regulatory relationships between specific kinases, phosphatases, and phosphoinositide subpools are not clear. We identified myotubularin (mtm), a Drosophila melanogast...

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Detalles Bibliográficos
Autores principales: Velichkova, Michaella, Juan, Joe, Kadandale, Pavan, Jean, Steve, Ribeiro, Inês, Raman, Vignesh, Stefan, Chris, Kiger, Amy A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2922644/
https://www.ncbi.nlm.nih.gov/pubmed/20696708
http://dx.doi.org/10.1083/jcb.200911020