Cargando…
Combinatorial profiling of chromatin-binding modules reveals multi-site discrimination
Specific interactions between post-translational modifications (PTMs) and chromatin-binding proteins are central to the idea of a ‘histone code’. Here, a 5000-member, PTM-randomized, combinatorial peptide library based on the N-terminus of histone H3 was utilized to interrogate multi-site specificit...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2010
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2922993/ https://www.ncbi.nlm.nih.gov/pubmed/20190764 http://dx.doi.org/10.1038/nchembio.319 |