Cargando…
Antagonistic role of hnRNP A1 and KSRP in the regulation of Let-7a biogenesis
The pluripotency promoting proteins Lin28a and Lin28b act as posttranscriptional repressors of let-7 miRNA biogenesis in undifferentiated embryonic stem cells. The levels of mature let-7a differ substantially in cells lacking Lin28 expression, indicating the existence of additional mechanism(s) of p...
| Autores principales: | , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2010
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2923024/ https://www.ncbi.nlm.nih.gov/pubmed/20639884 http://dx.doi.org/10.1038/nsmb.1874 |