Generation of human induced pluripotent stem cells by simple transient transfection of plasmid DNA encoding reprogramming factors

BACKGROUND: The use of lentiviruses to reprogram human somatic cells into induced pluripotent stem (iPS) cells could limit their therapeutic usefulness due to the integration of viral DNA sequences into the genome of the recipient cell. Recent work has demonstrated that human iPS cells can be genera...

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Detalles Bibliográficos
Autores principales: Si-Tayeb, Karim, Noto, Fallon K, Sepac, Ana, Sedlic, Filip, Bosnjak, Zeljko J, Lough, John W, Duncan, Stephen A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2923111/
https://www.ncbi.nlm.nih.gov/pubmed/20682060
http://dx.doi.org/10.1186/1471-213X-10-81

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2923111/
https://www.ncbi.nlm.nih.gov/pubmed/20682060
http://dx.doi.org/10.1186/1471-213X-10-81

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