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Generation of human induced pluripotent stem cells by simple transient transfection of plasmid DNA encoding reprogramming factors
BACKGROUND: The use of lentiviruses to reprogram human somatic cells into induced pluripotent stem (iPS) cells could limit their therapeutic usefulness due to the integration of viral DNA sequences into the genome of the recipient cell. Recent work has demonstrated that human iPS cells can be genera...
Autores principales: | Si-Tayeb, Karim, Noto, Fallon K, Sepac, Ana, Sedlic, Filip, Bosnjak, Zeljko J, Lough, John W, Duncan, Stephen A |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2923111/ https://www.ncbi.nlm.nih.gov/pubmed/20682060 http://dx.doi.org/10.1186/1471-213X-10-81 |
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